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Updated: May 6, 2026

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation

Published on: June 3, 2018

Temporary decrease in microvascular tissue saturation after transcatheter aortic valve implantation.

Manuel Stern¹, Sven Baasen¹, Patricia Wischmann¹

¹Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine University, Duesseldorf, Germany.

Clinical Hemorheology and Microcirculation

|June 29, 2024

Summary

This summary is machine-generated.

Transcatheter aortic valve implantation (TAVI) temporarily reduces peripheral microvascular tissue saturation (StO2). This microcirculation change is linked to kidney function and returns to baseline post-procedure.

Keywords:

Microcirculation microvascular tissue saturation near-infrared spectroscopy transcatheter aortic valve implantation

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Area of Science:

Cardiovascular Medicine
Medical Devices
Microcirculation Research

Background:

Limited data exists on transcatheter aortic valve implantation's (TAVI) impact on peripheral microcirculation.
Peripheral microvascular tissue saturation (StO2) is a key indicator of tissue perfusion.

Purpose of the Study:

To evaluate changes in peripheral microvascular tissue saturation (StO2) before and after TAVI.
To correlate StO2 changes with central/peripheral hemodynamics, cardiac function, and renal function.

Main Methods:

Prospective, single-center study comparing TAVI patients with a cardiac catheterization control group.
Assessed cardiac output (echocardiography), blood pressure, arterial stiffness, and StO2 (near-infrared spectroscopy).
Monitored renal function via creatinine levels pre- and post-procedure.

Main Results:

TAVI significantly increased cardiac output but decreased peripheral StO2 and hemodynamic parameters.
Peripheral StO2 levels returned to baseline at follow-up.
Decreased StO2 post-TAVI was negatively associated with elevated creatinine levels, indicating impaired renal function.

Conclusions:

Transcatheter aortic valve implantation induces a transient reduction in microvascular tissue saturation.
This microcirculatory effect is associated with renal function status in patients undergoing TAVI.