Related Experiment Video
Updated: Jun 16, 2026
07:40
A Murine Model of Subarachnoid Hemorrhage
Published on: November 21, 2013
19.7K
Chiari malformation presenting with subarachnoid hemorrhage: a case report
Samantha Schimmel1, Molly Monsour1, Davide Marco Croci2
1University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Neurocirugia (English Edition)
|June 29, 2024
Summary
Chiari malformation (CM) is rare in adults. This case report details an unusual presentation of CM type I with syringomyelia in a 65-year-old female, successfully treated with surgery.
Area of Science:
- Neurology
- Neurosurgery
- Radiology
Background:
- Chiari malformations (CM) are typically diagnosed in younger individuals, with adult incidence reported at 0.77%.
- Cerebrospinal fluid (CSF) obstruction at the cervicomedullary junction in CM can lead to syringomyelia and increased intracranial pressure (ICP).
Observation:
- A 65-year-old female presented with angionegative subarachnoid hemorrhage (SAH).
- The patient was newly diagnosed with Chiari malformation type I (CM I) with concomitant syringomyelia.
- Cranial imaging ruled out aneurysms or vascular malformations as the cause of SAH.
Findings:
- The patient underwent a suboccipital craniectomy with C1 laminectomy for Chiari decompression.
- Surgical intervention resulted in no complications.
- Post-operative improvement in the patient's symptoms was observed.
Implications:
- This case highlights the atypical presentation of CM in an elderly patient.
- It underscores the importance of considering CM in adult patients with neurological symptoms, even with unusual initial presentations like SAH.
- Surgical decompression remains an effective treatment for symptomatic CM with syringomyelia in adult populations.
Keywords:
C1 laminectomyChiari malformationHemorragia subaracnoideoLaminectomía de C1Malformación de ChiariSubarachnoid hemorrhageSyrinxMore Related Videos
Related Concept Videos
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
01:17Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
01:29Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
01:14Increased Intracranial Pressure l: Introduction
Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
01:29Increased Intracranial Pressure ll: Pathophysiology
Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...