Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Teratogenicity01:07

Teratogenicity

2.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.4K
Meiosis vs. Mitosis02:57

Meiosis vs. Mitosis

55.0K
Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
55.0K
Bone Disorders01:29

Bone Disorders

3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

5.9K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
5.9K
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

927
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
927
Sutures of the Skull01:22

Sutures of the Skull

6.6K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
6.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rates and predictors of intraventricular hemorrhage in the ventfirst trial with comparison to a contemporaneous cohort.

Journal of perinatology : official journal of the California Perinatal Association·2026
Same author

MRI in Sheep Model for Myelomeningocele Repair Using a Novel Polymer and Other Dural Patches.

Prenatal diagnosis·2026
Same author

Neonatal brain abnormalities predict preschool executive functioning performance in children born very preterm.

Developmental psychology·2026
Same author

Fetal cardiac masses.

Pediatric radiology·2025
Same author

Fetal MRI findings in conjoined twin pregnancies.

Pediatric radiology·2025
Same author

Slice-to-Volume Reconstruction of Fetal Brain MR Imaging in Clinical Practice.

AJNR. American journal of neuroradiology·2025

Related Experiment Video

Updated: Jun 22, 2025

Murine Fetal Echocardiography
08:04

Murine Fetal Echocardiography

Published on: February 15, 2013

17.3K

Fetal Skeletal Dysplasia.

Beth M Kline-Fath1

  • 1Department of Radiology, M.L. 5031, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

Magnetic Resonance Imaging Clinics of North America
|June 29, 2024
PubMed
Summary

Skeletal dysplasias are rare genetic disorders. An algorithm using ultrasound and MRI aids in diagnosing these conditions, enabling genetic testing and counseling for families.

Area of Science:

  • Medical Genetics
  • Radiology
  • Prenatal Diagnosis

Background:

  • Skeletal dysplasias (SDs) encompass a wide spectrum of genetic conditions.
  • Accurate diagnosis of SDs is challenging due to their rarity and diverse clinical manifestations.

Purpose of the Study:

  • To present an approach for diagnosing skeletal dysplasias prenatally.
  • To facilitate genetic testing and counseling for affected families.

Main Methods:

  • Utilizing a combination of sonographic and magnetic resonance (MR) imaging techniques.
  • Developing an algorithm based on imaging findings and knowledge of common SD presentations.

Main Results:

  • The proposed algorithm aids in the diagnosis of various skeletal dysplasias.
Keywords:
MRIPrenatalSkeletal dysplasiaUltrasound

More Related Videos

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse
08:19

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse

Published on: December 16, 2022

1.8K
Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound 30/45MHZ System
07:34

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound 30/45MHZ System

Published on: May 5, 2018

11.6K

Related Experiment Videos

Last Updated: Jun 22, 2025

Murine Fetal Echocardiography
08:04

Murine Fetal Echocardiography

Published on: February 15, 2013

17.3K
A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse
08:19

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse

Published on: December 16, 2022

1.8K
Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound 30/45MHZ System
07:34

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound 30/45MHZ System

Published on: May 5, 2018

11.6K
  • Integration of imaging data with clinical knowledge improves diagnostic accuracy.

    • Conclusions:

    • An algorithmic approach integrating prenatal imaging (ultrasound and MRI) can significantly improve the diagnosis of skeletal dysplasias.
    • This diagnostic pathway supports timely genetic testing and counseling, benefiting families with suspected skeletal dysplasias.