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A Fabrication Method for Highly Stretchable Conductors with Silver Nanowires
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Stretchable Tissue-Like Gold Nanowire Composites with Long-Term Stability for Neural Interfaces.

Laura Seufert1, Mohammed Elmahmoudy1, Charlotte Theunis1

  • 1Laboratory of Organic Electronics, Department of Science and Technology, Linköping University, Norrköping, 602 21, Sweden.

Small (Weinheim an Der Bergstrasse, Germany)
|June 30, 2024
PubMed
Summary

Researchers developed new soft, conductive nanocomposites for neural interfaces. These gold nanowire composites offer improved biocompatibility and chronic stability, enabling better nerve stimulation and recording.

Keywords:
cuff electrodesgold nanowiresneural interfacessoft electronicsstretchable electronics

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Area of Science:

  • Biomaterials Science
  • Neuroscience Engineering
  • Nanotechnology

Background:

  • Soft and stretchable nanocomposites are crucial for neural interfaces to mimic neural tissue properties.
  • Existing materials often fail to combine low Young's modulus, high conductivity, stretchability, and biocompatibility.
  • Current nanocomposites lack the necessary combination of softness and high conductivity for effective neural interfacing.

Purpose of the Study:

  • To develop a scalable synthesis route for soft, conductive nanocomposites for neural interfaces.
  • To address the limitations of current materials in achieving both softness and high conductivity.
  • To create advanced neural interface materials with improved biocompatibility and chronic stability.

Main Methods:

  • Developed a scalable synthesis route using polymeric reducing agents for gold nanowires (AuNWs).
  • Fabricated AuNW-silicone composites with controllable AuNW dimensions and excellent biocompatibility.
  • Engineered soft multielectrode cuffs using the developed nanocomposite material.

Main Results:

  • Achieved nerve-like softness (250 kPa), high conductivity (16,000 S cm⁻¹), and reversible stretchability in AuNW-silicone composites.
  • Demonstrated selective functional stimulation and recording of sensory stimuli in rat sciatic nerves using the multielectrode cuffs.
  • Showcased accelerated lifetime stability exceeding 3 years for the neural interface devices.

Conclusions:

  • The developed scalable synthesis method provides a chemically stable alternative to silver nanowires (AgNWs).
  • The AuNW-silicone nanocomposites meet critical requirements for advanced neural interfaces.
  • Enabled new applications in electronics, biomedical devices, and electrochemistry due to material properties and stability.