Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

  1. Home
  3. Research Domains
  5. Engineering
  7. Materials Engineering
  9. Wearable Materials
  11. Stretchable Tissue-like Gold Nanowire Composites With Long-term Stability For Neural Interfaces

Stretchable Tissue-Like Gold Nanowire Composites with Long-Term Stability for Neural Interfaces

Laura Seufert1, Mohammed Elmahmoudy1, Charlotte Theunis1

  • 1Laboratory of Organic Electronics, Department of Science and Technology, Linköping University, Norrköping, 602 21, Sweden.

Small (Weinheim an Der Bergstrasse, Germany)
|June 30, 2024

Related Experiment Videos

A Fabrication Method for Highly Stretchable Conductors with Silver Nanowires
07:50

A Fabrication Method for Highly Stretchable Conductors with Silver Nanowires

Published on: January 21, 2016

9.9K
Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive
06:40

Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive

Published on: September 27, 2013

14.8K
Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
08:54

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

10.7K

View abstract on PubMed

Summary
This summary is machine-generated.

Researchers developed new soft, conductive nanocomposites for neural interfaces. These gold nanowire composites offer improved biocompatibility and chronic stability, enabling better nerve stimulation and recording.

Area of Science:

  • Biomaterials Science
  • Neuroscience Engineering
  • Nanotechnology

Background:

  • Soft and stretchable nanocomposites are crucial for neural interfaces to mimic neural tissue properties.
  • Existing materials often fail to combine low Young's modulus, high conductivity, stretchability, and biocompatibility.
  • Current nanocomposites lack the necessary combination of softness and high conductivity for effective neural interfacing.

Purpose of the Study:

  • To develop a scalable synthesis route for soft, conductive nanocomposites for neural interfaces.
  • To address the limitations of current materials in achieving both softness and high conductivity.
  • To create advanced neural interface materials with improved biocompatibility and chronic stability.

Main Methods:

  • Developed a scalable synthesis route using polymeric reducing agents for gold nanowires (AuNWs).
Keywords:
cuff electrodesgold nanowiresneural interfacessoft electronics

Related Experiment Videos

A Fabrication Method for Highly Stretchable Conductors with Silver Nanowires
07:50

A Fabrication Method for Highly Stretchable Conductors with Silver Nanowires

Published on: January 21, 2016

9.9K
Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive
06:40

Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive

Published on: September 27, 2013

14.8K
Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
08:54

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

10.7K
  • Fabricated AuNW-silicone composites with controllable AuNW dimensions and excellent biocompatibility.
  • Engineered soft multielectrode cuffs using the developed nanocomposite material.

    • Main Results:

    • Achieved nerve-like softness (250 kPa), high conductivity (16,000 S cm⁻¹), and reversible stretchability in AuNW-silicone composites.
    • Demonstrated selective functional stimulation and recording of sensory stimuli in rat sciatic nerves using the multielectrode cuffs.
    • Showcased accelerated lifetime stability exceeding 3 years for the neural interface devices.

    Conclusions:

    • The developed scalable synthesis method provides a chemically stable alternative to silver nanowires (AgNWs).
    • The AuNW-silicone nanocomposites meet critical requirements for advanced neural interfaces.
    • Enabled new applications in electronics, biomedical devices, and electrochemistry due to material properties and stability.
    stretchable electronics