Related Experiment Video
Updated: Jun 22, 2025

10:03
A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
Published on: February 28, 2013
25.8K
START Diabetes Prevention: A Multi-Level Strategy for Primary Care Clinics.
Medrxiv : the Preprint Server for Health Sciences
|July 1, 2024
Summary
A multi-level intervention significantly increased prediabetes treatment uptake in primary care. This approach improved patient understanding and clinician engagement, proving effective and feasible for preventing diabetes.
Area of Science:
- Primary care interventions
- Diabetes prevention
- Public health
Background:
- Prediabetes affects over a third of US adults, yet fewer than 5% receive treatment.
- Existing interventions often overlook clinician and system-level barriers to prediabetes care.
Purpose of the Study:
- To evaluate the effectiveness of a multi-level intervention on increasing prediabetes treatment uptake within a primary care setting.
Main Methods:
- A pragmatic study of the START (Screen, Test, Act, Refer and Treat) Diabetes Prevention intervention was conducted over 12 months.
- The intervention involved a structured workflow, shared decision-making tools, and EHR clinical decision support.
- Uptake of prediabetes treatment was defined as DPP referral, metformin prescription, or MNT referral within 30 days of a primary care visit.
Main Results:
- Prediabetes treatment uptake was significantly higher in the intervention clinic (11.6%) compared to the control clinic (6.7%, p<0.001).
- Patients in the intervention group reported more discussions about prediabetes with their clinicians (60% vs. 48%, p=0.002).
- Clinicians found the START intervention acceptable and useful, with enhanced patient understanding and engagement.
Conclusions:
- A low-touch, multi-level intervention effectively increases prediabetes treatment uptake in primary care.
- The intervention demonstrated feasibility and acceptability for clinicians.
- Enhanced patient understanding and communication regarding prediabetes were observed.
Related Concept Videos
Diabetes: Management and Pharmacotherapy
256
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
256
Preventive Healthcare Services
1.0K
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
1.0K
Diabetes Mellitus: Type 2 and Gestational
2.3K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.3K
Levels of Health Promotion and Illness Prevention
12.6K
Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
In primary prevention, actions taken before disease onset prevent the disease from...
12.6K
Diabetes Mellitus: Overview and Type I Subtype
2.5K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.5K
Diabetes: Symptoms, Diagnosis, and Complications
521
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
521

