Related Experiment Video
Updated: Jul 14, 2026

18:25
Orthotopic Liver Transplantation in Rats
Published on: July 1, 2012
30.0K
Cold ischemia time in liver transplantation: An overview
Manuela Cesaretti1,2, Alessandro Izzo1, Roberta Anna Pellegrino1
1Department of HPB and Liver Transplantation, Brotzu Hospital, Cagliari 09122, Italy.
World Journal of Hepatology
|July 1, 2024
Summary
Cold ischemia time (CIT) in liver transplantation, defined as the period between graft cross-clamping and reperfusion, is a critical risk factor. This review examines CIT components and preservation strategies to improve graft survival.
Area of Science:
- Transplantation immunology
- Organ preservation
- Surgical risk factors
Background:
- Static cold storage is the standard for liver graft preservation.
- Cold ischemia time (CIT) is a key donor-related risk factor influencing graft and recipient survival.
- Increasing use of marginal liver grafts necessitates analysis of CIT factors.
Related Concept Videos
Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

