Safety monitoring of precautionary third dose of COVID-19 vaccines in a district in Northern India
View abstract on PubMed
Summary
This summary is machine-generated.COVID-19 booster shots are safe, with very few adverse events reported. However, acceptance rates for these crucial precautionary doses remain low compared to initial vaccinations.
Area Of Science
- Immunization and Public Health
- Vaccine Safety Surveillance
- Infectious Disease Epidemiology
Background
- The COVID-19 pandemic, caused by SARS-CoV-2, prompted global vaccination efforts.
- India initiated its vaccination program in January 2021 with Covishield and Covaxin, later introducing booster doses.
Purpose Of The Study
- To assess the safety and adverse events following the administration of COVID-19 precautionary booster doses.
- To evaluate the acceptance rate of COVID-19 booster doses in the Karnal district.
Main Methods
- A descriptive observational study was conducted at COVID-19 vaccination centers in Karnal.
- Adverse drug reactions (ADRs) were collected using a standardized reporting form.
- Causality assessment of reported ADRs was performed using the WHO-UMC scale.
Main Results
- A total of 72,853 individuals received the COVID-19 booster dose.
- Only three ADRs were reported following booster vaccination, all classified as unlikely.
- Booster dose administration numbers were significantly lower than first and second doses.
Conclusions
- COVID-19 booster doses demonstrate a favorable safety profile.
- Low acceptance rates for booster doses were observed, indicating a need for further public health strategies.

