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Related Concept Videos

Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
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Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
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Diabetes: Symptoms, Diagnosis, and Complications01:15

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Updated: Jun 22, 2025

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
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COVID-19 and Type 1 Diabetes.

Liala Burmeister

    Pediatric Annals
    |July 1, 2024
    PubMed
    Summary

    The COVID-19 pandemic saw a rise in new-onset type 1 diabetes (T1D) in children, especially adolescents. Research explores the link between COVID-19 infection and the development of T1D in pediatric patients.

    Area of Science:

    • Pediatric Endocrinology
    • Infectious Diseases
    • Immunology

    Background:

    • The COVID-19 pandemic presented unique challenges for pediatric populations, with generally milder acute illness compared to adults.
    • A notable post-infection complication observed in children and adolescents is the increased incidence of new-onset type 1 diabetes (T1D).

    Purpose of the Study:

    • To review the epidemiology of COVID-19 and type 1 diabetes (T1D) during the pandemic.
    • To explore the proposed mechanisms linking COVID-19 infection to T1D development in pediatric patients.
    • To highlight the need for further research on the long-term effects of COVID-19 on T1D in children and adolescents.

    Main Methods:

    • This is a review article, synthesizing existing literature and data.
    • The review examines epidemiological trends of COVID-19 and T1D in pediatric populations.

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  • Proposed etiological mechanisms are discussed based on current scientific understanding.

    • Main Results:

    • Pediatric COVID-19 cases typically presented with milder illness than adults.
    • An increased incidence of new-onset type 1 diabetes (T1D) was observed in children and adolescents following COVID-19 infection.
    • Specific demographic groups, particularly adolescents, showed a higher susceptibility.

    Conclusions:

    • COVID-19 infection is increasingly suspected as a contributing factor to the development of type 1 diabetes in pediatric patients.
    • Understanding the precise mechanisms is crucial for managing and potentially preventing T1D post-COVID-19.
    • Long-term studies are essential to fully comprehend the pandemic's impact on pediatric T1D incidence and outcomes.