Related Experiment Video
Updated: Jun 22, 2025

Methods for Detecting Cough and Airway Inflammation in Mice
Published on: August 2, 2024
Lower Income, Smoking, Cardiopulmonary Comorbidities, and Higher Symptom Burden Influence the Occurrence of Cough in
Joosun Shin1, Marilyn J Hammer2, Mary E Cooley2
1University of California, San Francisco.
Objectives:
To identify subgroups of patients with distinct cough occurrence profiles and evaluate for differences among these subgroups.
Sample & Setting:
Outpatients receiving chemotherapy (N = 1,338) completed questionnaires six times over two chemotherapy cycles.
Methods & Variables:
Occurrence of cough was assessed using the Memorial Symptom Assessment Scale. Latent class analysis was used to identify subgroups with distinct cough occurrence profiles. Parametric and nonparametric tests were used to evaluate for differences.
Results:
Four distinct cough profiles were identified (None, Decreasing, Increasing, and High). Risk factors associated with membership in the High class included lower annual household income; history of smoking; self-reported diagnoses of lung disease, heart disease, and back pain; and having lung cancer.
Implications For Nursing:
Clinicians need to assess all patients with cancer for cough and provide targeted interventions.
Related Concept Videos
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Other Pulmonary Disorders
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Chronic Obstructive Pulmonary Disease-I: Introduction
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation

