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Updated: Jun 20, 2026

Fast and Accurate Exhaled Breath Ammonia Measurement
Published on: June 11, 2014
An exhaled breath gas sensor system for near-infrared ammonia measurement and kidney diagnostics
Kaiyuan Zheng1, Lei Zhang1, Shuo Leng2
1State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, 2699 Qianjin Street, Changchun 130012, China; Kaiyuan Zheng and Lei Zhang contributed equally to this work.
Abstract:
Breath analysis enables rapid, noninvasive diagnosis of human health by identifying and quantifying exhaled biomarker. Here, we demonstrated an exhaled breath sensing method using the near-infrared laser spectroscopy, and sub parts-per-million (ppm) level ammonia detection inside the exhaled gas was achieved employing a distributed feedback laser centered at 1512 nm and Kalman filtering algorithm. Integration of the ammonia sensor was realized for exhaled breath analysis of kidney patients, and a dual operation mechanism with static and dynamic modes was proposed to make this method applicable for real-time and comprehensive pre-diagnosis of kidney disease.
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