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Updated: Aug 14, 2026

Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation
Published on: March 7, 2018
Detection of a fundamental modular format common to transfer and ribosomal RNAs: second-order spectral analysis
Abstract:
Second-order spectral analysis is used to detect rigorously and to characterize the principal periodicities in the positions of conserved sequences common to tRNAs and rRNAs. It is shown that the shared periodicity having the largest spectral amplitude is 9, followed by 8 and 10, thus forming a closed triad of significant multiplets centered at 9 bases. This conclusion is proposed to reflect a closed triadic set of fundamental tandem repeat lengths in a class of ancestral macromolecules possessing a restricted sequence symmetry. The terms "remanent" and "archeomodular" are used to describe a relic modular format, traces of which are shown here to persist despite the changes that have occurred in the primary structures of ribonucleic acids during the course of their evolution.
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