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Updated: May 12, 2026

Isolation of Brain-infiltrating Leukocytes
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An unusual presentation of fungal brain abscess in immunocompetent host

Sajid Islam Bhatti1, Sidra German2, Tajammul Waqar3

  • 1Sajid Islam Bhatti Department of Nephrology, Sindh Institute of Urology and Transplantation (SIUT), Karachi. Pakistan.

Pakistan Journal of Medical Sciences
|July 2, 2024
PubMed

Insights

A rare case of multiple brain abscesses in an immunocompetent young female presented with unusual neurological symptoms and acute kidney injury. Prompt antifungal treatment and abscess drainage led to full recovery.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Nephrology

Background:

  • Brain abscesses are typically caused by infections or trauma.
  • This case involves multiple abscesses in an immunocompetent young female without typical risk factors.

Observation:

  • The patient presented with bilateral lower limb weakness, seizures, and fever.
  • Fungal brain abscesses led to acute kidney injury (AKI), requiring intermittent hemodialysis (IHD).

Findings:

  • Successful treatment involved abscess drainage and antifungal therapy.
  • The patient showed significant clinical and radiological improvement, with resolution of AKI.

Implications:

  • Highlights the importance of considering fungal infections in immunocompetent individuals with unusual neurological presentations.
  • Emphasizes the potential for severe systemic complications like AKI from brain abscesses.
  • Demonstrates the effectiveness of timely intervention in managing complex brain abscess cases.
Keywords:
Acute Kidney Injury (AKI)Kidney Replacement Therapy (KRT)

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