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When the Belly Looks Okay but Is Actually Not: A Case of Hepatoblastoma in a Well-Appearing Child
Margaret A Uchefuna1, Imoh L Ebong1, Lamyaa Mohamed1
1Department of Pediatrics, NYC Health + Hospitals/Woodhull Medical Center, New York, USA.
Insights
Hepatoblastoma, a rare pediatric liver tumor, often presents with advanced disease. Early diagnosis through imaging and lab tests is crucial for effective treatment and management in children.
Area of Science:
- Pediatric Oncology
- Hepatobiliary Diseases
Background:
- Hepatoblastoma is a primary malignant liver tumor in children.
- Genetic and intrauterine factors contribute to its development.
- Often diagnosed at advanced stages with metastasis.
Abstract:
Hepatoblastoma is one of the pediatric tumors with genetic and intrauterine risk factors. It is typically asymptomatic at diagnosis, at which time most patients have metastasis to the lungs and are in an advanced stage of liver disease. We report an interesting case of a 13-month-old child who presented with a one-month history of abdominal distention. A review of the systems was unremarkable but a physical examination revealed a well-appearing child with abdominal distention, normal vital signs, and an abdominal mass. Abdominal imaging revealed a well-defined heterogeneously-enhancing mass arising from the right hepatic lobe and laboratory results were consistent with a diagnosis of hepatoblastoma. The mass was resected and the patient underwent chemotherapy with continued follow-up management. We shed light on pediatric hepatoblastoma and its clinical presentation, pathology, and laboratory and imaging findings, to aid clinicians in diagnosing the condition correctly.

