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Uremic acquired cystic disease of kidney

I Ishikawa

    Urology
    |August 1, 1985
    PubMed

    Insights

    Uremic acquired cystic kidney disease (ACDK) is common in male hemodialysis patients, increasing kidney cancer risk. Regular screening and renal transplantation are recommended for managing ACDK and its complications.

    Area of Science:

    • Nephrology
    • Oncology
    • Urology

    Background:

    • Uremic acquired cystic kidney disease (ACDK) is a condition affecting kidneys in patients with end-stage renal insufficiency.
    • ACDK is particularly prevalent in male patients undergoing long-term hemodialysis.
    • ACDK is associated with complications such as tumors, bleeding, and abscesses, with kidney cancer being a significant concern.

    Purpose of the Study:

    • To highlight the high incidence of ACDK in hemodialysis patients.
    • To emphasize the association between ACDK and kidney cancer.
    • To recommend screening and management strategies for ACDK.

    Main Methods:

    • Review of incidence rates of ACDK, tumors, and kidney cancer in hemodialysis patients.
    • Clinical presentation analysis for ACDK and its complications.
    • Evaluation of diagnostic tools like ultrasonic examination and CT scans.
    • Assessment of treatment outcomes, including renal transplantation.

    Main Results:

    • ACDK occurs in 47.1% of hemodialysis patients.
    • Tumors and kidney cancer are observed in 4.8% and 1.5% of hemodialysis patients, respectively.
    • Symptoms like gross hematuria, flank pain, decreased hematocrit, and fever may indicate ACDK or complications.

    Conclusions:

    • ACDK poses a significant risk for kidney cancer, even without overt symptoms.
    • Regular screening via ultrasound or CT scans is crucial for early detection.
    • Renal transplantation can lead to regression of ACDK.
    • ACDK warrants classification as a distinct renal cystic disease and serves as a model for studying cyst and tumor development.

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