[Micromodification of the leukocyte adherence inhibition test for cancer patients]

A simplified micromodification of the leukocyte adherence inhibition (LAI) test using both leukocytes and lymphocytes from peripheral blood of cancer patients is discussed. Data on oncoimmunologic specificity and cellular mechanisms underlying the proposed procedure as well as the results of a comparative study of LAI factor-producing T-cell and immunoregulatory (Tmu and T gamma) lymphocyte subpopulations in breast cancer patients are presented. The LAI-test micromodification may be adjunct in breast cancer diagnosis. It may be employed for monitoring T-cell specific immunity in cancer patients and further study of LAI factor-producing T-cells as a component of the structure of T-cell subpopulations.