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Related Experiment Video

Updated: Jun 22, 2025

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
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Stereoelectroencephalography-guided radiofrequency thermocoagulation.

Guillaume Dannhoff1, Luca Fumagalli1, Sarah Ferrand-Sorbets2

  • 1Departments of Neurosurgery.

Neurosurgical Focus: Video
|July 3, 2024
PubMed
Summary

Stereoelectroencephalography-guided radiofrequency thermocoagulation (SEEG-RFTC) offers epilepsy management options, including curative, diagnostic, and palliative treatments. This awake procedure shows promise, with 81% responder rates in specific conditions like periventricular nodular heterotopia.

Keywords:
SEEGepilepsy surgerystereoelectroencephalographythermocoagulation

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Area of Science:

  • Neurosurgery
  • Epileptology
  • Neurology

Background:

  • Stereoelectroencephalography-guided radiofrequency thermocoagulation (SEEG-RFTC) is a neurosurgical technique for epilepsy management.
  • It offers a versatile approach with potential for curative, diagnostic, and palliative outcomes.

Purpose of the Study:

  • To evaluate the efficacy and applications of SEEG-RFTC in managing epilepsy.
  • To highlight its role in targeting ictal onset zones and epileptic networks.

Main Methods:

  • The procedure involves awake patients undergoing continuous neurological evaluation.
  • Key parameters monitored include impedance, time, and energy delivered during radiofrequency thermocoagulation.
  • Lesions are strategically placed to target epileptic networks or small-volume ictal onset zones.

Main Results:

  • SEEG-RFTC can be curative for small-volume ictal onset zones.
  • It serves as a diagnostic tool by assessing coagulation effects on seizures and mapping epileptic networks.
  • Palliative treatment is achievable through multiple lesions in extensive epileptic networks.
  • High response rates, up to 81%, are observed in specific conditions such as periventricular nodular heterotopia.

Conclusions:

  • SEEG-RFTC is an effective and adaptable tool in the neurosurgeon's armamentarium for epilepsy management.
  • The technique demonstrates potential for favorable outcomes in selected epilepsy cases, particularly periventricular nodular heterotopia.