Profile and Prognostic Impact of Multimorbidity in Elderly Patients with Heart Failure: Are there Differences between...

Area of Science:

• Cardiology
• Geriatrics
• Clinical Research

Background:

• Heart failure (HF) is a growing concern, particularly in the elderly.
• Elderly patients, especially women, are underrepresented in clinical trials and registries.
• Comorbidities in older adults significantly impact HF presentation and outcomes.

Purpose of the Study:

• To review the specific characteristics of elderly women with heart failure.
• To investigate disparities in treatment and outcomes compared to men.
• To identify knowledge gaps regarding HF management in this demographic.

Main Methods:

• Review of existing clinical trials and registries.
• Analysis of demographic and clinical data of elderly HF patients.
• Comparison of treatment patterns and outcomes between sexes.

Main Results:

• Women with HF are typically older, with more non-cardiovascular comorbidities and preserved ventricular function.
• Despite a better prognosis (lower hospitalization and mortality), women receive less guideline-recommended therapy.
• Self-perceived quality of life is worse in women with HF.

Conclusions:

• Elderly women with HF present differently and have a better prognosis than men.
• There are significant treatment disparities, with women less likely to receive guideline-recommended interventions.
• Further research is crucial to understand and address these gaps in evidence and care.