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  9. Infant And Child Health
  11. Recent Increase In Infant Pertussis Cases In Europe And The Critical Importance Of Antenatal Immunizations: We Must Do Better…now.

Recent increase in infant pertussis cases in Europe and the critical importance of antenatal immunizations: We must do better…now.

Asma Khalil1, Athina Samara2, Helen Campbell3

  • 1Fetal Medicine Unit, St George's Hospital, St George's University of London, London, UK; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, London, UK; The Royal College of Obstetricians and Gynaecologists, London, UK.

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
|July 3, 2024

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View abstract on PubMed

Summary
This summary is machine-generated.

Global pertussis (whooping cough) cases are rising due to decreased immunity from COVID-19 pandemic disruptions. Maternal immunization and timely infant vaccination are crucial for protecting vulnerable newborns from severe disease.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Immunology

Background:

  • Pertussis (whooping cough) outbreaks are increasing globally.
  • Reduced circulation of Bordetella pertussis during the COVID-19 pandemic has lowered population immunity.
  • This susceptibility has amplified the natural cyclical peaks in pertussis activity.

Purpose of the Study:

  • To analyze the recent increase in pertussis cases.
  • To highlight the impact of pandemic-related immuneWaning on population susceptibility.
  • To emphasize the importance of maternal immunization and timely infant vaccination.

Main Methods:

  • Analysis of pertussis case data from Northern and Southern hemispheres.
  • Assessment of the impact of reduced Bordetella pertussis circulation on population immunity.
Keywords:
Antenatal immunizationPertussisPregnancyVaccine hesitancy

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  • Review of immunization strategies for pertussis prevention.

    • Main Results:

    • Significant increase in pertussis cases observed globally.
    • Population susceptibility to pertussis has heightened due to decreased immune stimulation.
    • Maternal immunization is highly effective in protecting young infants.

    Conclusions:

    • The rise in pertussis cases is linked to diminished immunity post-pandemic.
    • Maintaining high immunization rates, especially maternal vaccination, is vital for infant protection.
    • Timely infant vaccination is critical to prevent severe pertussis disease.
    Whooping cough