Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epistasis01:39

Epistasis

46.6K
In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
46.6K
Epistasis Analysis01:09

Epistasis Analysis

5.0K
Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...
5.0K
Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

6.5K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
6.5K
Pigmentation01:19

Pigmentation

2.4K
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
2.4K
Genetic Lingo01:11

Genetic Lingo

102.6K
Overview
102.6K
Genetic Variation01:25

Genetic Variation

273
Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
Genes exist in different versions called alleles,...
273

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Emerging technologies for the discovery of biosynthetic genes in plants.

Natural product reports·2026
Same author

Phylogenetic based dissection of eukaryotic Mo-insertase functionality: From mechanism to complex assembly.

PloS one·2026
Same author

DupyliCate: mining, classifying, and characterizing gene duplications.

Scientific reports·2026
Same author

Genome sequence of the ornamental plant Digitalis purpurea reveals the molecular basis of flower color and morphology variation.

BMC genomics·2026
Same author

Cookbook for plant genome sequences.

BMC genomics·2026
Same author

Diversity and ecological functions of anthocyanins.

BMC plant biology·2025
Same journal

Retraction Note: An ABRE-binding factor, OSBZ8, is highly expressed in salt tolerant cultivars than in salt sensitive cultivars of indica rice.

BMC plant biology·2026
Same journal

Extending calla lily vase life using silver nitrate, silver nanoparticles, and chlorogenic acid: a novel strategy to sustain xylem conductivity and antioxidant defense.

BMC plant biology·2026
Same journal

Exploring the impact of light spectra on growth: unveiling the role of LED light in modulating phytochemical responses of feverfew (Tanacetum parthenium L.).

BMC plant biology·2026
Same journal

Genetic mosaic and population stratification of wild pomegranate (Punica granatum) across the Pir Panjal range.

BMC plant biology·2026
Same journal

Strategies of photosynthetic physiology in response to karst habitats and rainfall allocation have maintained the morphology and function of Fraxinus malacophylla seedlings.

BMC plant biology·2026
Same journal

PD-ViCo: an explainable AI-based contrastive captioner vision transformer with patch dropout for multi-class brinjal disease classification.

BMC plant biology·2026
See all related articles

Related Experiment Video

Updated: Jun 22, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

18.2K

Genetic factors explaining anthocyanin pigmentation differences.

Maria F Marin-Recinos1, Boas Pucker2

  • 1Plant Biotechnology and Bioinformatics, Institute of Plant Biology and BRICS, TU Braunschweig, Braunschweig, Germany.

BMC Plant Biology
|July 3, 2024
PubMed
Summary
This summary is machine-generated.

MYB transcription factors are the primary drivers of anthocyanin color variation in plants, frequently explaining differences between varieties. These regulatory genes, along with structural genes like DFR, are key to understanding plant pigmentation evolution.

Keywords:
AnthocyaninsDFRFlavonoid biosynthesisGene expressionMYBSystematic comparisonTranscription factorTranscriptome

More Related Videos

Quantifying Abdominal Pigmentation in Drosophila melanogaster
08:41

Quantifying Abdominal Pigmentation in Drosophila melanogaster

Published on: June 1, 2017

9.0K
Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics
08:09

Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics

Published on: June 17, 2012

19.7K

Related Experiment Videos

Last Updated: Jun 22, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

18.2K
Quantifying Abdominal Pigmentation in Drosophila melanogaster
08:41

Quantifying Abdominal Pigmentation in Drosophila melanogaster

Published on: June 1, 2017

9.0K
Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics
08:09

Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics

Published on: June 17, 2012

19.7K

Area of Science:

  • Plant biology
  • Genetics
  • Evolutionary biology

Background:

  • Anthocyanins are plant pigments crucial for coloration, reproduction, and stress protection.
  • Anthocyanin biosynthesis is well-studied due to visible mutant phenotypes and involves complex gene regulation.
  • Genes for anthocyanin biosynthesis are controlled by MYB, bHLH, and WD40 transcription factor complexes.

Purpose of the Study:

  • To systematically compare genetic factors causing anthocyanin loss in diverse plant species.
  • To identify genes responsible for intraspecific pigmentation differences using transcriptomic data.
  • To quantify the contribution of structural and regulatory genes to plant color variation.

Main Methods:

  • Literature screening for genetic factors of anthocyanin loss.
  • Reanalysis of transcriptomic data from four studies.
  • Systematic comparison of pigmented vs. non-pigmented plant varieties across taxonomic diversity.

Main Results:

  • Transcription factor differences are the most common cause of pigmentation variation within species.
  • MYB genes are significantly more likely than bHLH or WD40 genes to explain pigmentation differences.
  • DFR genes are most frequently associated with anthocyanin loss among structural genes.

Conclusions:

  • Transcriptional regulation is highly susceptible to evolutionary changes, driving novel coloration phenotypes.
  • MYB transcription factors play a particularly significant and prevalent role in the MBW complex specificity.
  • Understanding these genetic mechanisms is crucial for plant coloration evolution.