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Long-term outcomes following mitral valve replacement in children at heart center Leipzig: a 20-year analysis

Katja Schumacher1, Mateo Marin-Cuartas1, Muhammed Ikbal Aydin1

  • 1Department of Cardiac Surgery, Leipzig Heart Center, Leipzig University, Leipzig, Germany.

Journal of Cardiothoracic Surgery
|July 3, 2024
PubMed

Insights

Mitral valve replacement in children with severe valve disease offers good long-term survival and freedom from reoperation when repair is not possible. This surgical option provides favorable outcomes for pediatric patients.

Area of Science:

  • Pediatric Cardiac Surgery
  • Cardiovascular Research
  • Medical Device Outcomes

Background:

  • Mitral valve repair is preferred for pediatric mitral valve disease.
  • Severe dysplastic valves may necessitate mitral valve replacement.
  • Long-term outcomes of pediatric mitral valve replacement are analyzed.

Purpose of the Study:

  • To evaluate long-term outcomes of mitral valve replacement in children.
  • To assess survival and reoperation rates after pediatric mitral valve replacement.
  • To determine the efficacy of mitral valve replacement when repair is not feasible.

Main Methods:

  • Retrospective analysis of prospectively collected data from 41 pediatric patients.
  • Study period: February 2001 to February 2021.
  • Primary outcomes: in-hospital mortality, long-term survival, freedom from reoperation.

Main Results:

  • Low in-hospital mortality (4.9%) and early re-exploration rates.
  • Median follow-up of 11 years.
  • 15-year survival was 80.8%; 15-year freedom from reoperation was 42.5%.

Conclusions:

  • Mitral valve replacement is a viable surgical alternative for pediatric mitral valve disease when repair is not feasible.
  • The procedure demonstrates good early and long-term outcomes.
  • Offers a beneficial option for children requiring valve replacement.
Abstract

Keywords:
Mitral valve disease, mitral valve surgeryMitral valve replacementPediatric cardiac surgery

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