Related Experiment Video
Updated: Jun 22, 2025

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
Published on: November 3, 2023
Associated Factors of Patients' Survival in Out of Hospital Cardiac Arrest; a Cross-sectional Study
Liang Ke1, Pui I Ieong2, Kaye E Brock1,3
1Macao Hypertension League, China.
Insights
Out-of-hospital cardiac arrest survival in Macao is predicted by shockable rhythm, male sex, faster emergency medical service response, and early defibrillation. Public awareness and education are crucial for improving outcomes.
Area of Science:
- Emergency Medicine
- Cardiology
- Public Health
Background:
- Out-of-hospital cardiac arrest (OHCA) presents a significant public health challenge, particularly in Chinese populations.
- Macao Special Administrative Region (SAR), China, has an increasing prevalence of OHCA, necessitating focused research on survival factors.
Purpose of the Study:
- To investigate prehospital factors associated with survival to hospital admission and discharge in adult OHCA cases in Macao.
- To identify key predictors that can inform public health strategies and emergency medical services (EMS).
Main Methods:
- Retrospective analysis of 904 adult OHCA cases in Macao.
- Data collected from medical records and the Macao Fire Services Bureau.
- Multivariate logistic regression used to analyze demographic and prehospital factors influencing survival.
Main Results:
- Initial shockable cardiac rhythm was the strongest predictor for survival to both admission (OR=3.57) and discharge (OR=12.40).
- Male sex (OR=1.63) and lower EMS response time (OR=1.62) were associated with increased survival to hospital admission.
- Access to prehospital defibrillation showed a significant 4-fold association with survival to hospital discharge (OR=4.25).
Conclusions:
- Key predictors of OHCA survival include shockable rhythm, male sex, rapid EMS response, and prompt defibrillation.
- Findings highlight the need for enhanced public awareness and targeted education to improve OHCA survival rates.
Introduction:
Chinese populations have an increasingly high prevalence of cardiac arrest. This study aimed to investigate the prehospital associated factors of survival to hospital admission and discharge among out-of-hospital cardiac arrest (OHCA) adult cases in Macao Special Administrative Region (SAR), China.
Methods:
Baseline characteristics as well as prehospital factors of OHCA patients were collected from publicly accessible medical records and Macao Fire Services Bureau, China. Demographic and other prehospital OHCA characteristics of patients who survived to hospital admission and discharge were analyzed using multivariate logistic regression analysis.
Results:
A total of 904 cases with a mean age of 74.2±17.3 (range: 18-106) years were included (78%>65 years, 62% male). Initial shockable cardiac rhythm was the strongest predictor for survival to both hospital admission (OR=3.57, 95% CI: 2.26-5.63; p<0.001) and discharge (OR=12.40, 95% CI: 5.70-26.96; p<0.001). Being male (OR=1.63, 95% CI:1.08-2.46; p =0.021) and the lower emergency medical service (EMS) response time (OR=1.62, 95% CI: 1.12-2.34; p =0.010) were also associated with a 2-fold association with survival to hospital admission. In addition, access to prehospital defibrillation (OR=4.25, 95% CI: 1.78-10.12; p <0.001) had a 4-fold association with survival to hospital discharge. None of these associations substantively increased with age.
Conclusion:
The major OHCA predictors of survival were initial shockable cardiac rhythm, being male, lower EMS response time, and access to prehospital defibrillation. These findings indicate a need for increased public awareness and more education.
Related Concept Videos
Pathophysiology of Heart Failure
Assumptions of Survival Analysis
Pathophysiology of Cardiac Performance
Cancer Survival Analysis
Actuarial Approach
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...

