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Schwannoma in the Rectum: A Case Report
Mikayla Hobbs1, Ryan Denis1, Martin Felix1
1General Surgery, St. George's University School of Medicine, St. George, GRD.
Cureus
|July 4, 2024
Summary
A rare rectal schwannoma was diagnosed in a woman with a history of Helicobacter pylori infection. This case highlights the importance of considering schwannomas in rectal mass differentials.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Oncology
Background:
- A woman in her 60s with a history of recurrent Helicobacter pylori (H. pylori) infection presented with a rectal mass.
- Colonoscopy identified a rectal mass, and initial biopsy showed no dysplasia or malignancy.
Observation:
- The mass was a solid, submucosal rectal lesion.
- Immunohistochemistry revealed positivity for SOX10 and S100.
Findings:
- The final pathology confirmed the diagnosis of a rectal schwannoma.
- The immunohistochemical markers SOX10 and S100 supported the schwannoma diagnosis.
Implications:
- This case underscores the necessity of including schwannomas in the differential diagnosis for rectal masses.
- Early consideration of rare diagnoses like schwannoma is crucial for accurate patient management.

