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Updated: Jul 23, 2026
Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold
Published on: October 23, 2015
Experimental Modeling of Cranial Injury and Defect Reconstruction Using Superconstructive Polymers (PEEK)
F M Shakova1, G A Romanova2, S Yu Khashirova3
1Research Institute of General Pathology and Pathophysiology, Moscow, Russia. shakova.fatima@yandex.ru.
Abstract:
Experimental model of resection craniotomy with subsequent reconstruction of the defect with a polymer implant enables comprehensive assessment of functional and ultrastructural changes during replacement of the damaged tissue. Reconstruction of a skull defect was accompanied by transient motor disturbance in the acute period and did not cause functional disorders and neurological deficits in a delayed period. Histological examination of osteal and brain tissue revealed no pathological reactions that could be associated with the response to the chemical components of the implant.
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