Evaluation and management of knee osteoarthritis
- Siyi Zhu 1,2, Wenchun Qu 3, Chengqi He 1,2
- Siyi Zhu 1,2, Wenchun Qu 3, Chengqi He 1,2
- 1Rehabilitation Medicine Center and Institute of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, China.
- 2Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, China.
- 3Department of Pain Medicine, Mayo Clinic, Jacksonville, Florida, USA.
- 0Rehabilitation Medicine Center and Institute of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, China.
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View abstract on PubMed
Summary
This summary is machine-generated.Knee osteoarthritis (KOA) is a major cause of disability, with rising incidence. Early, non-drug treatments like exercise and weight management are key for managing KOA symptoms and improving joint function.
Area Of Science
- Orthopedics
- Rheumatology
- Public Health
Background
- Knee osteoarthritis (KOA) is a leading cause of global disability, projected to increase significantly by 2050.
- Understanding KOA's complex pathogenesis, including mechanical, inflammatory, and metabolic factors, is crucial for effective management.
Purpose Of The Study
- To provide a comprehensive, updated systematic review of knee osteoarthritis (KOA).
- To elucidate KOA's pathogenesis, risk factors, clinical features, and current treatment strategies.
Main Methods
- A systematic review of literature was conducted up to February 26, 2024.
- Key aspects analyzed include etiology, risk factors, diagnosis, and management paradigms.
Main Results
- KOA involves mechanical, inflammatory, and metabolic disturbances; key risk factors include age, obesity, and prior knee injury.
- Diagnosis relies on clinical assessment, with imaging used conditionally; rehabilitation assessments are vital.
- Non-pharmacological treatments (education, exercise, weight management) are primary, with medications and interventions as adjuncts.
Conclusions
- Early diagnosis and proactive management, prioritizing non-pharmacological approaches, are essential for alleviating KOA symptoms and enhancing function.
- Individualized treatment plans and integrated rehabilitation assessments are crucial for optimizing patient outcomes.
- Further research is needed to refine KOA prevention and improve long-term management strategies.
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