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Measuring Dengue Virus RNA in the Culture Supernatant of Infected Cells by Real-time Quantitative Polymerase Chain Reaction
Published on: November 1, 2018
Neurodengue, a narrative review of the literature
Abelardo Queiroz Campos Araujo1,2, Marco Antonio Lima1,3, Marcus Tulius Teixeira Silva1,4
1Fundação Oswaldo Cruz, Instituto Nacional de Doenças Infecciosas, Laboratório de Pesquisa Clínica em Neuroinfecção.
Abstract:
Dengue fever (DF) is the most frequent arboviral disease globally. Deforestation, armed conflicts, and climate change have caused an unprecedented global spread of DF, raising concerns in healthcare systems worldwide. Systemic manifestations of the disease range from mild to severe and, in some cases, can lead to death. Although neurological complications have been reported over the last few decades, they are often neglected or underreported. The present narrative review aims to describe the most important central and peripheral nervous system complications and provide guidance to neurologists in terms of diagnosis and management.
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