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The complex link between sleep-disordered breathing and asthma control in pediatric patients: A cross-sectional study

Cristian Locci1, Mariangela V Puci2, Laura Saderi2

  • 1Pediatric Clinic, Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.

Respiratory Medicine
|July 4, 2024
PubMed

Insights

Sleep-disordered breathing (SDB) is common in children with asthma, impacting their asthma control and quality of life (QoL). Uncontrolled asthma increases SDB risk, warranting further investigation.

Area of Science:

  • Pediatric Pulmonology
  • Sleep Medicine
  • Allergy and Immunology

Background:

  • Asthma and sleep-disordered breathing (SDB) in children can negatively impact quality of life (QoL).
  • SDB may also complicate the effective management of pediatric asthma.

Purpose of the Study:

  • To determine the prevalence of SDB in asthmatic children.
  • To assess the association between SDB and asthma control.
  • To identify risk factors for SDB and evaluate the impact of asthma control and SDB on QoL.

Main Methods:

  • Recruited 78 asthmatic children (aged 5-12 years).
  • Assessed SDB using the Pediatric Sleep Questionnaire (PSQ).
  • Evaluated asthma control with the Childhood Asthma Control Test (C-ACT) and QoL with the Pediatric Quality of Life Inventory (PedsQL).

Main Results:

  • SDB prevalence was 37.2%, significantly higher in children with uncontrolled asthma (60.1%) versus well-controlled asthma (27.3%).
  • Uncontrolled asthma (C-ACT ≤19) showed a 4.15-fold increased risk of SDB.
  • Asthmatic children with SDB had lower C-ACT and PedsQL scores, indicating poorer asthma control and QoL.

Conclusions:

  • SDB significantly affects asthma control and QoL in children.
  • Asthmatic children with uncontrolled asthma are at higher risk for SDB.
  • Referral for polysomnography is recommended for asthmatic children with uncontrolled asthma to rule out underlying SDB.
Abstract

Keywords:
AsthmaChildrenObstructive sleep apneaQuality of lifeSleep-disordered breathing

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