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Soft peripheral contact lens for eye elongation control (SPACE): 1-year results of a double-blinded randomized
Shan-Chih Lee1, Min-Yen Hsu2, Shih-Chien Huang3
1Department of Medical Imaging And Radiological Sciences, Chung Shan Medical University, Taichung, Taiwan.
Insights
This study found that multifocal soft contact lenses showed similar myopia control efficacy to dual-focus lenses in children over one year. Both lens types effectively slowed myopia progression, indicating comparable safety and effectiveness for slowing refractive error and axial length changes.
Area of Science:
- Ophthalmology
- Optometry
- Pediatric Eye Care
Background:
- Myopia progression is a growing concern in children.
- Soft multifocal contact lenses are being investigated as a myopia control strategy.
- Understanding the efficacy of different lens designs is crucial for clinical practice.
Purpose of the Study:
- To evaluate the safety and efficacy of daily disposable soft multifocal contact lenses in slowing myopia progression in children.
- To compare the myopia control effects of a specific multifocal lens (Pegavision) against a dual-focus lens (MiSight).
Main Methods:
- A one-year prospective, randomized, double-masked clinical trial involving 115 children aged 8-15 years.
- Participants wore either Pegavision multifocal or MiSight dual-focus daily disposable soft contact lenses.
- Ocular measurements included refractive error, visual acuity, contrast sensitivity, and axial length.
Main Results:
- Both lens groups showed comparable increases in spherical equivalent refractive error and axial length after one year.
- No statistically significant differences in myopia progression were observed between the multifocal and dual-focus lens groups.
- Axial length increased by approximately 0.23 mm in both eyes for both lens types.
Conclusions:
- Daily disposable soft multifocal contact lenses demonstrate similar myopia control efficacy to dual-focus lenses.
- The findings suggest comparable safety and effectiveness in managing myopia progression in pediatric populations.
- Further research may explore long-term outcomes and different multifocal lens designs.
Purpose:
To examine the safety and efficacy of soft multifocal contact lenses on slowing the rate of myopia progression.
Methods:
A prospective, randomized, double-masked clinical trial was conducted including 115 children (55 boys and 60 girls) aged 8 to 15 years. Children were assigned to wear one of two daily disposable soft contact lens designs; a multifocal design (Pegavision) or a dual-focus design (MiSight, Coopervision) in both eyes for at least 8 h per day for one year. All contact lenses were replaced on a daily basis. Measurements were obtained using a logMAR vision meter, including objective refraction, handheld retinoscopy, high (96 %) and low (12 %) contrast sensitivity, and distance and near visual acuity. Axial length was measured every 6 months.
Results:
After one year, the spherical equivalent refractive error and axial length of the experimental group (Pegavision) increased by -0.50 ± 0.48 D and 0.24 ± 0.16 mm, respectively, in the right eye and -0.47 ± 0.37 D and 0.23 ± 0.16 mm, respectively, in the left eye. The spherical equivalent refractive error and axial length of the control group (MiSight) increased by -0.48 ± 0.47 D and 0.22 ± 0.13 mm, respectively, in the right eye and by -0.50 ± 0.44 D and 0.23 ± 0.14 mm, respectively, in the left eye, with no significant differences observed between the two lens types.
Conclusions:
The one-year results from this clinical trial show that the multifocal soft contact lenses used in the experimental group have a similar myopia control efficacy with respect to spherical equivalent refraction and axial length elongation as a commercially available dual focus soft contact lens design.
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