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Lifestyle predictors of colorectal cancer in European populations: a systematic review

  • 0Unit of Non-Comunicable Diseases, Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Bmj Nutrition, Prevention & Health +

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July 5, 2024

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July 5, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

Lifestyle factors like BMI, smoking, and alcohol are key predictors in European colorectal cancer (CRC) risk models. Standardizing these predictors can improve public health models and encourage screening participation.

Area Of Science

  • Oncology
  • Public Health
  • Epidemiology

Background

  • Colorectal cancer (CRC) is a leading cancer in Europe, with unhealthy lifestyles contributing to one-fifth of cases.
  • Risk prediction models are crucial for identifying high-risk individuals and informing prevention strategies.

Purpose Of The Study

  • To identify lifestyle predictors used in European CRC risk models.
  • To characterize parameter values for understanding their predictive contribution.

Main Methods

  • Systematic review of PubMed and Web of Science (Jan 2000-Aug 2021).
  • Inclusion criteria: European adult populations, non-invasive predictors, reported estimates and uncertainty.
  • Visualization of predictors using forest plots for comparison.

Main Results

  • 21 CRC risk prediction models were eligible (16 studies); 11 validated in Europe.
  • Body mass index (BMI), smoking, and alcohol were the most common lifestyle predictors.
  • Dietary factors were less frequently included; detailed data collection improved predictive contribution.

Conclusions

  • Identifying high-risk groups via lifestyle data can promote screening and lifestyle changes, reducing CRC burden.
  • Standardizing commonly shared lifestyle predictors in public health models can enhance their uptake and effectiveness.

Keywords:

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