Related Experiment Video
Updated: Aug 19, 2026

Protocols for Vaginal Inoculation and Sample Collection in the Experimental Mouse Model of Candida vaginitis
Published on: December 8, 2011
Treatment of vaginal candidosis using clotrimazole vaginal cream: single dose versus 3-day therapy
Abstract:
The effect of using a single dose of 10% clotrimazole cream was compared with that of using a twice-daily application of 2% clotrimazole cream for 3 days in 111 women with mycologically proven vaginal candidosis. The results, analyzed for 55 patients in each group, showed that 1 week after starting treatment, negative cultures were recorded for 91% of the patients who received single-dose therapy and 96% of patients treated with the 3-day regimen. Five weeks after treatment started, the figures were 84% and 81%, respectively, showing that both regimens were equally effective. No adverse events were recorded for either preparation.
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