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Related Experiment Video

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Modified Heterotopic Hindlimb Osteomyocutaneous Flap Model in the Rat for Translational Vascularized Composite Allotransplantation Research

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Published on: April 26, 2019

Modified Reverse Hatchet Flap for Ablepharon-Macrostomia Syndrome.

Yash J Vaishnav^1,2, Louise A Mawn^1,2

¹Department of Ophthalmology and Visual Sciences, Vanderbilt University School of Medicine.

Ophthalmic Plastic and Reconstructive Surgery

|July 5, 2024

Summary

Ablepharon-macrostomia syndrome, a rare disorder, requires prompt intervention. A novel multiplanar eyelid reconstruction technique using modified flaps and skin grafts offers a promising solution for vision preservation.

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Area of Science:

Ophthalmology
Medical Genetics
Plastic Surgery

Background:

Ablepharon-macrostomia syndrome is a rare genetic disorder.
It is characterized by TWIST2 mutations and anterior lamellar dysgenesis.
Early intervention is crucial to prevent severe ocular complications like exposure keratopathy and vision loss.

Purpose of the Study:

To present a novel surgical approach for multiplanar eyelid reconstruction in patients with ablepharon-macrostomia syndrome.
To address the challenges posed by anterior lamellar dysgenesis and eyelid abnormalities.

Main Methods:

A modified reverse hatchet flap was utilized for reconstruction of one lower eyelid.
Division at the eyelid margin and recession of eyelid retractors were performed.
Preputial skin grafting was employed for anterior lamellar restoration in the remaining three eyelids.

Main Results:

The described surgical technique allowed for comprehensive eyelid reconstruction.
This approach addressed both structural eyelid abnormalities and anterior lamellar defects.

Conclusions:

This novel multiplanar eyelid reconstruction technique offers a viable solution for ablepharon-macrostomia syndrome.
The combined use of modified flaps and skin grafting shows potential for restoring eyelid function and preserving vision.