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Updated: Aug 11, 2026

Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
Successful Management of Cherubism Patient With Staged Bone Grafting and Fat Grafting
Jonathan Butts1, Kalyan Dadireddy, Jessica A Ching
1Division of Plastic Surgery, University of Florida, Gainsville, FL.
Abstract:
Cherubism is a rare hereditary dysplasia of the craniofacial skeleton with unpredictable course and controversial management. The authors report a case managed at the onset with limited mandibular resection and primary autogenous bone grafting, as well as staged secondary fat grafting for contour definition. Over 5 years, the patient demonstrated no recurrence of deformity except for mild hypoplasia, which was improved with fat grafting. The advantages of this early treatment were the ability to address the social stigma and anxiety at a young age versus conservative management strategies with minimal comorbidity.
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