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Updated: Jun 21, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

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Prevalence and Risk Factors of Prenatal and Postnatal Depressive Symptoms in Babol Pregnancy Mental Health Registry:

Shahnaz Barat1, Shirin Shahrokhi2, Seyyedeh Mahboubeh Mirtabar3

  • 1Department of Obstetrics and Gynecology, Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

International Journal of Fertility & Sterility
|July 8, 2024
PubMed

Insights

Prenatal and postnatal depression (PND) affects maternal and child health. High parity, early pregnancy, and high-risk pregnancies are key risk factors for antenatal depression.

Area of Science:

  • Perinatal mental health
  • Reproductive health
  • Clinical psychology

Background:

  • Prenatal and postnatal depression (PND) is linked to adverse outcomes for mothers, fetuses, and children.
  • Identifying prevalence and risk factors for PND is crucial for timely intervention.

Purpose of the Study:

  • To determine the prevalence of depressive symptoms during pregnancy and postpartum.
  • To identify risk factors associated with prenatal and postnatal depressive symptoms.

Main Methods:

  • A cross-sectional, hospital-based survey of 2305 women (18-48 years) was conducted.
  • Data collected via demographics and depression questionnaires, including the Edinburg Postnatal Depression Scale (EPDS).
  • Statistical analyses included t-tests, ANOVA, and multiple logistic regressions.

Main Results:

  • The prevalence of depressive symptoms was 19.8% in pregnant women versus 11.6% in postpartum women.
  • Risk factors for antenatal depression included high parity (≥4), early gestational age (≤12 weeks or 21-27 weeks), and high-risk pregnancy.
  • No significant risk factors were identified for postnatal depressive symptoms in this study.

Conclusions:

  • Screening for prenatal and postnatal depressive symptoms is recommended.
  • Particular attention should be given to women in the first and second trimesters, those with high parity, and high-risk pregnancies.
Abstract

Keywords:
DepressionPostnatalPrenatalPrevalenceRisk Factors

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