Femoro-popliteal endovascular interventions
Azat Chinaliyev1,2, Samat Saparbayev3, Bazylbek Zhakiyev1
1Department of Surgical Diseases No 2, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Summary
Peripheral artery disease (PAD) treatment lacks a clear standard due to varied endovascular intervention (EVI) outcomes. Head-to-head trials are needed to compare EVIs for femoro-popliteal PAD.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Endovascular Interventions
Background:
- Peripheral artery disease (PAD) is a significant global health issue, predicting mortality and morbidity.
- Endovascular interventions (EVIs) offer therapeutic options for PAD when drug therapy is insufficient.
- Existing randomized controlled trials (RCTs) show efficacy for atherectomy, stents, and medicated balloons over traditional angioplasty.
Purpose of the Study:
- To review femoro-popliteal EVIs for PAD.
- To highlight evidence supporting various EVIs.
- To explain the rationale behind current EVI usage in PAD treatment.
Main Methods:
- Review of randomized controlled trials (RCTs) comparing different endovascular interventions (EVIs) for femoro-popliteal PAD.
- Analysis of evidence supporting atherectomy, stents, and medicated balloons.
- Examination of factors influencing EVI selection and outcomes.
Main Results:
- RCTs demonstrate the efficacy of various EVIs compared to transluminal angioplasty.
- Lack of head-to-head comparative studies between different EVIs hinders establishing a standard treatment.
- Variable outcomes in functional capacity and quality of life (QoL) complicate EVI superiority assessment.
Conclusions:
- A clear standard treatment for PAD remains undefined due to insufficient comparative EVI data.
- Future PAD clinical trials should prioritize head-to-head comparisons of different EVIs.
- Further research is necessary to determine the optimal EVI for femoro-popliteal PAD.
