Mild Encephalopathy/Encephalitis With Reversible Splenial Lesion Associated With Meningitis Related to Mumps Disease:

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Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
26:48

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis

Published on: July 4, 2007

18.0K

Aziz Ahizoune1, Yassine El-Adraoui1, Ahmed Bourazza1

  • 1Department of Neurology and Neurophysiology, Mohamed V Military Teaching Hospital, Mohamed V University, Rabat, MAR.

Cureus
|July 8, 2024
PubMed

Insights

Mumps infection can cause Mild Encephalitis/Encephalopathy with Reversible Splenial Lesion (MERS) in adults, a rare but treatable condition. This case highlights favorable outcomes with symptomatic and antiviral treatments.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Mild Encephalitis/Encephalopathy with Reversible Splenial Lesion (MERS) is a neurological condition characterized by reversible brain lesions.
  • Infectious etiologies are common triggers for MERS, particularly mumps in children.
  • MERS is infrequently reported in adults, with limited case documentation.

Observation:

  • A 23-year-old male presented with mumps, exhibiting symptoms of meningeal syndrome, dizziness, seizures, and orchitis.
  • Brain MRI revealed characteristic MERS lesions in the splenium of the corpus callosum.
  • Cerebrospinal fluid analysis indicated lymphocytic pleocytosis, consistent with viral meningitis.

Findings:

  • The patient was diagnosed with mumps complicated by MERS, meningitis, and orchitis.
  • Treatment involved symptomatic management and antiviral therapy.
  • Neurological and clinical manifestations showed gradual resolution without sequelae.

Implications:

  • This case expands the understanding of mumps as a potential cause of MERS in adults.
  • It underscores the importance of considering MERS in adults presenting with neurological symptoms and mumps.
  • The favorable outcome emphasizes the effectiveness of timely and appropriate medical intervention.
Keywords:
aseptic meningitismersmild encephalopathy/encephalitis with reversible splenial lesionmumpsparotitis

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