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Medications and Orthodontic Tooth Movement: What Accelerates and Diminishes Tooth Movement?
Rawan Alrehaili1, Ashraf Alhujaili2, Shahad Alharbi3
1Dentistry, Private Practice, Medina, SAU.
Cureus
|July 8, 2024
Summary
Orthodontic tooth movement relies on bone remodeling influenced by applied forces. This review examines how common medications may affect this process, impacting treatment outcomes.
Area of Science:
- Orthodontics
- Periodontology
- Pharmacology
Background:
- Orthodontic tooth movement is a complex biological process driven by bone remodeling.
- This remodeling involves inflammatory mediators and cellular signaling pathways.
- Medications can influence the molecular pathways regulating periodontal tissue homeostasis.
Purpose of the Study:
- To explore the effects of commonly prescribed medications on orthodontic tooth movement.
- To review existing evidence on medication impacts on tooth movement.
- To identify future research directions in this area.
Main Methods:
- Literature review of studies investigating medication effects on orthodontic tooth movement.
- Analysis of evidence regarding molecular pathways and cellular regulation.
- Synthesis of findings on commonly prescribed medications.
Main Results:
- Medications influencing periodontal homeostasis or clastic cell regulation can modulate tooth movement.
- Clinicians must be aware of patient medication use due to potential treatment impacts.
- Evidence suggests a link between certain medications and altered rates of tooth movement.
Conclusions:
- Understanding medication effects is crucial for effective orthodontic treatment planning.
- Further research is needed to elucidate specific drug interactions and their clinical significance.
- Awareness of patient pharmacotherapy is essential for optimizing orthodontic outcomes.
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