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Updated: Jun 21, 2025

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Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
Published on: April 9, 2019
21.5K
Targeted biopsy of the prostate
David W Schroeder1, Bryan R Foster1, Daniel J Young1
1Department of Diagnostic Radiology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mail Code: L340, Portland, OR, 97239, United States.
Abdominal Radiology (New York)
|July 8, 2024
Summary
Multiparametric MRI (mpMRI) now reliably detects prostate cancer tumors. Targeted biopsy methods, like MRI-ultrasound fusion, are replacing traditional biopsies for more accurate diagnosis.
Area of Science:
- Urology
- Radiology
- Oncology
Background:
- Multiparametric MRI (mpMRI) has advanced prostate cancer diagnosis over 30 years.
- mpMRI reliably depicts the dominant tumor in most prostate cancer cases.
- Traditional blind systematic biopsy is being superseded by MRI-guided approaches.
Purpose of the Study:
- To review the current status of targeted prostate biopsy techniques.
- To compare the relative accuracy of different MRI-guided biopsy methods.
- To highlight areas requiring further research in prostate cancer diagnosis.
Main Methods:
- Review of recent advancements in targeted prostate biopsy.
- Analysis of software-assisted MRI-ultrasound (US) fusion biopsy.
- Evaluation of direct MRI-guided in-bore biopsy techniques.
- Presentation of results from large multicenter trials.
Main Results:
- Targeted biopsy methods are increasingly replacing traditional systematic biopsy.
- MRI-ultrasound fusion and in-bore MRI-guided biopsies show promise in accuracy.
- Multicenter trials provide critical data on technique efficacy.
Conclusions:
- Targeted biopsy represents a significant shift in prostate cancer diagnosis.
- The accuracy of various targeted biopsy techniques is a key focus.
- Further research is needed to address remaining questions in the field.

