Related Experiment Video
Updated: Jun 21, 2025
06:34
A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
10.0K
Buckwheat Allergy in Asia.
Naoki Kajita1, Koichi Yoshida2
1Department of Allergy, Tokyo Metropolitan Children Medical Center, Musashidai Fuchu, Tokyo, 183-8561, Japan. naoki_kajita@tmhp.jp.
Current Allergy and Asthma Reports
|July 8, 2024
Summary
Buckwheat allergy, including immediate reactions, exercise-induced anaphylaxis, and enterocolitis syndrome, is prevalent in Asia. Fag e 3-specific IgE and skin prick tests aid diagnosis.
Area of Science:
- Food allergy research
- Clinical immunology
- Gastroenterology
Background:
- Buckwheat allergy is a significant health concern, particularly in Asian populations.
- Understanding the different clinical presentations, including immediate food allergy, food-dependent exercise-induced anaphylaxis (FDEIA), and food protein-induced enterocolitis syndrome (FPIES), is crucial.
Purpose of the Study:
- To review and compare data on buckwheat allergy from Asian and non-Asian countries.
- To elucidate the current knowledge on buckwheat allergy, identify research gaps, and propose future research directions.
Main Methods:
- Literature review comparing studies on buckwheat allergy prevalence and characteristics in Asia versus other regions.
- Analysis of implicated buckwheat components and diagnostic utility of serological markers and skin tests.
Main Results:
- Most research on buckwheat allergy originates from Japan and Korea, with limited studies elsewhere.
- Seven components of common buckwheat (Fagopyrum esculentum) and four of Tartary buckwheat (Fagopyrum tartaricum) are linked to allergies.
- While buckwheat-specific IgE (BW-sIgE) has limited diagnostic value for immediate allergy, Fag e 3-specific IgE and skin prick tests show diagnostic utility.
Conclusions:
- Buckwheat allergy presents diverse clinical manifestations, with regional variations in research focus.
- Further research is needed to enhance the understanding and management of buckwheat allergy globally.
- Specific biomarkers like Fag e 3-IgE and established tests like skin prick tests are valuable diagnostic tools.
