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Intravitreal Bevacizumab in Management of Persistent Secondary Macular Hole with Epiretinal Proliferation
Ugyen Zangmo1, Sushma Jayanna, Mahesh P Shanmugam
1Jigme Dorji Wangchuk National Referral Hospital, Thimphu, Bhutan.
Background:
Aetiology for non-closure of full-thickness macular hole (FTMH) becomes crucial in determining the method of effective mode of intervention. Association of epiretinal proliferation (ERP) along with full-thickness macular hole (FTMH) have shown poorer anatomic and visual outcomes after surgical intervention. Various surgical techniques have been described in literature for treatment of persistent MH.
Case:
We report a A 60-year-old female patient with FTMH secondary to branched retinal vein occlusion (BRVO) initially associated with ERP.
Observations:
She was successfully managed by treating with combination of intravitreal injection of off label bevacizumab (Avastin) (1.25 mg/0.05 ml) and pure gas of SF6 (1 cc) under topical anaesthesia after an initial surgical intervention.
Conclusion:
Presence of ERP in retinal vein occlusion cases needs closer and frequent follow up. IVB can be used as an adjunct in treating secondary MH.

