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The interplay between diabetes Mellitus and soft tissue infections in general surgical patients

Stephanie Cheng1, Benjamin Rui-Min Poh1, Vivyan Wei Yen Tay1

  • 1Department of General Surgery, Singapore General Hospital, Singapore, Singapore.

BMC Endocrine Disorders
|July 8, 2024
PubMed
Abstract

Insights

Diabetes mellitus (DM) increases soft tissue infection (STI) risk and severity. Diabetic patients experience longer hospital stays, larger wounds, and more complex treatments for STIs.

Area of Science:

  • General Surgery
  • Infectious Diseases
  • Endocrinology

Background:

  • Diabetes mellitus (DM) is a global pandemic impacting 500 million individuals.
  • DM is linked to increased susceptibility to soft tissue infections (STIs).
  • Limited literature exists on DM's impact on STI presentation, severity, and healing in surgical patients.

Purpose of the Study:

  • To investigate the association between DM and STI outcomes in general surgical patients.
  • To analyze the presentation, severity, and healing of STIs in diabetic versus non-diabetic patients.

Main Methods:

  • Retrospective review of patients admitted with STIs over 12 months.
  • Analysis of patient demographics and surgical outcomes.

Main Results:

  • DM is an independent risk factor for longer length of stay (LOS).
  • Diabetic patients had higher BMI, larger abscesses, and longer LOS (4.4 vs. 2.9 days).
  • Diabetic patients underwent more debridement, negative pressure wound therapy, and re-operations; they were twice as likely to present with carbuncles.

Conclusions:

  • STIs in diabetic patients represent a significant health burden.
  • Surgeons should counsel diabetic patients on lifestyle modification and glucose control.
  • Collaboration with primary care providers is crucial for reducing future STI admissions.
Keywords:
AbscessAcute care surgeryDiabetesInfectionSoft tissue infections

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