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Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model
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"Very" Very Late Stent Thrombosis: A Detailed Look at Two Cases

Adhvithi Pingili1, Shiavax J Rao1, Taha Khalid2

  • 1Internal Medicine, MedStar Union Memorial Hospital, Baltimore, USA.

Cureus
|July 9, 2024
PubMed

Insights

Very late stent thrombosis (VVLST), occurring over five years after coronary stenting, is exceptionally rare. This study presents two new cases, highlighting the need for further research into this serious complication of percutaneous coronary intervention.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology

Background:

  • Percutaneous coronary intervention (PCI) with stenting is a cornerstone in treating coronary artery disease.
  • Stent thrombosis (STh), a serious complication, can occur years after implantation.
  • Very late stent thrombosis (VVLST) is defined as STh occurring more than five years post-PCI.

Observation:

  • VVLST is an extremely rare event, with limited documented cases.
  • This report details two complex clinical cases of VVLST presenting as ST-elevation myocardial infarction.
  • The cases underscore the challenges in diagnosing and managing VVLST.

Findings:

  • The study reviews the epidemiology, pathophysiology, and clinical presentation of VVLST.
  • Diagnostic strategies and current treatment approaches for VVLST are discussed.
  • Associated complications and potential risk factors are highlighted.

Implications:

  • The rarity and severity of VVLST necessitate increased clinical awareness.
  • Further research is crucial to elucidate VVLST mechanisms and optimize prevention strategies.
  • Minimizing the risk of VVLST is essential for long-term patient outcomes after PCI.

Keywords:
coronary artery disease (cad)coronary stentcoronary stent thrombosisst-elevation myocardial infarction (stemi)very late stent thrombosis

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