Related Experiment Video

Updated: Jun 21, 2025

Visualizing Clathrin-mediated Endocytosis of G Protein-coupled Receptors at Single-event Resolution via TIRF Microscopy
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Visualizing Clathrin-mediated Endocytosis of G Protein-coupled Receptors at Single-event Resolution via TIRF Microscopy

Published on: October 20, 2014

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CCDC32 stabilizes clathrin-coated pits and drives their invagination

Ziyan Yang, Changsong Yang, Zheng Huang

    Biorxiv : the Preprint Server for Biology
    |July 9, 2024
    PubMed
    Summary

    CCDC32 is a novel protein crucial for clathrin-mediated endocytosis (CME) by stabilizing clathrin-coated pits. Mutations in CCDC32 impair AP2 binding, linking it to cardio-facio-neuro-developmental syndrome (CFNDS).

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