Clinicopathological correlation of a solitary choroidal tuberculoma

In a 34-year-old black man with pulmonary tuberculosis, a rapidly enlarging choroidal tuberculoma progressed to larger size, despite appropriate systemic anti-tuberculous therapy. The eye harboring the tuberculoma became blind and painful, and was subsequently enucleated. Conventional staining of tissue sections revealed a choroidal granuloma without evidence of organisms, but tubercle bacilli were demonstrated by fluorescence microscopy.