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A Strategy for Sensitive, Large Scale Quantitative Metabolomics
Published on: May 27, 2014
Metabolomics 2023 workshop report: moving toward consensus on best QA/QC practices in LC-MS-based untargeted
Jonathan D Mosley1, Warwick B Dunn2, Julia Kuligowski3
1Center for Environmental Measurement and Modeling, Environmental Protection Agency, Athens, GA, USA.
Introduction:
During the Metabolomics 2023 conference, the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) presented a QA/QC workshop for LC-MS-based untargeted metabolomics.
Objectives:
The Best Practices Working Group disseminated recent findings from community forums and discussed aspects to include in a living guidance document.
Methods:
Presentations focused on reference materials, data quality review, metabolite identification/annotation and quality assurance.
Results:
Live polling results and follow-up discussions offered a broad international perspective on QA/QC practices.
Conclusions:
Community input gathered from this workshop series is being used to shape the living guidance document, a continually evolving QA/QC best practices resource for metabolomics researchers.
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