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Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
Internet-Guided Cognitive Behavioral Therapy for Insomnia Among Patients With Traumatic Brain Injury: A Randomized
Molly E Malarkey1,2, Adele J Fu1,2, Noushin Mannan1,2
1The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc, Bethesda, Maryland.
Internet-guided cognitive-behavioral therapy for insomnia (eCBT-I) shows moderate feasibility and effectiveness for military personnel with traumatic brain injury (TBI). This approach offers a promising, accessible treatment for insomnia and depression in this population.
Area of Science:
- Sleep Medicine
- Neuroscience
- Military Health
Background:
- Insomnia is prevalent among military service members and veterans following traumatic brain injury (TBI).
- Traditional cognitive-behavioral therapy for insomnia (CBT-I) faces limitations in clinician availability, cost, and completion rates.
Purpose of the Study:
- To assess the feasibility and efficacy of internet-guided CBT-I (eCBT-I) for military personnel with insomnia and a history of TBI.
- To evaluate eCBT-I's impact on insomnia severity, depression, PTSD, sleep quality, and fatigue.
Main Methods:
- A randomized clinical trial involving military service members and veterans with mild TBI/concussion and moderate-to-severe insomnia.
- Participants were randomized to either 6-week internet-guided CBT-I (eCBT-I) or an online sleep education control group.
- Outcomes included changes in Insomnia Severity Index (ISI) scores and self-reported measures of depression, PTSD, sleep quality, and fatigue.
Main Results:
- eCBT-I demonstrated a statistically significant reduction in ISI scores compared to the control group (difference of 3.5, P=0.03).
- Improvements in insomnia severity correlated with reductions in depression symptoms (ρ=0.68), PTSD symptoms (ρ=0.36), and fatigue (ρ=-0.58).
- Completion rates were moderate, with 50 participants finishing post-intervention evaluations and 41 completing 3-month follow-up.
Conclusions:
- Fully remote eCBT-I is a feasible and effective intervention for insomnia and depression in military populations with TBI.
- eCBT-I presents a valuable, low-cost alternative to traditional CBT-I, addressing accessibility challenges.
- Future research should focus on optimizing study retention and incorporating objective sleep measures.
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