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Research Trends and Evolution in Radiogenomics (2005-2023): Bibliometric Analysis
Meng Wang1, Yun Peng2, Ya Wang2
1Department of Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.
Radiogenomics research is rapidly expanding, with the US and Netherlands leading influential studies. Current trends focus on using artificial intelligence and big data to predict tumor treatment responses.
Area of Science:
- Radiogenomics, integrating genomics and radiomics for precision medicine.
- Emerging field with significant growth in publications.
Background:
- Radiogenomics combines genomics with medical imaging (radiomics).
- It is a key approach for advancing precision medicine.
Purpose of the Study:
- To quantitatively analyze the research landscape of radiogenomics.
- To map its dynamic trends and evolutionary trajectory using bibliometrics.
Main Methods:
- Bibliometric analysis of 3237 papers from Web of Science Core Collection (up to 2023).
- Utilized Excel for publication trends, VOSviewer for network analysis, and CiteSpace for burst and timeline analysis.
Main Results:
- Increasing annual publication trend observed.
- China and the US lead in publications; US leads in citations; Netherlands leads in average citations per paper.
- Key research clusters include glioma, lung cancer, breast cancer, and artificial intelligence applications.
Conclusions:
- Radiogenomics is gaining global research interest, with the US and Netherlands as key contributors.
- AI-driven big data approaches for predicting tumor treatment response are a current research hotspot.
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