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A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications
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Casting a wider net: The clinical potential of EV transcriptomics in multi-analyte liquid biopsy
Yari Ciani1, Caterina Nardella1, Francesca Demichelis1
1Department of Cellular, Computational, and Integrative Biology (CIBIO), University of Trento, Trento, Italy.
Cancer Cell
|July 9, 2024
Abstract:
Cancer cells release cell-free DNA (cfDNA) and extracellular vesicles (EVs) into the bloodstream, allowing disease non-invasive monitoring. In this issue of Cancer Cell, Casanova-Salas et al. analyze cfDNA, EV-DNA, and EV-RNA in prostate cancer longitudinal cohorts treated with androgen receptor signaling inhibitors and taxanes, identifying signals reflecting tumor adaptation processes.
