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Updated: Aug 17, 2026

Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice
Published on: December 1, 2017
Clinical study of co-trimazine in urinary tract infections: a comparison with nitrofurantoin
Abstract:
Co-trimazine, a new preparation of sulphadiazine and trimethoprim, was compared with nitrofurantoin in a double-blind trial on patients with acute urinary tract infections. Co-trimazine had a bacteriological cure rate of 95% as compared to 88% for nitrofurantoin. There were no statistically significant differences in laboratory findings or in clinical side-effects between the two laboratory findings or in clinical side-effects between the two preparations. It was concluded that co-trimazine might constitute a valuable addition amongst drugs suitable for treatment of acute urinary tract infections.
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