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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
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[Beyond hypercoagulability in celiac disease]

C Álvarez-González1, J Espíldora-Hernández1, M A Sánchez-Chaparro2

  • 1Servicio de Medicina Interna, Hospital Universitario Virgen de la Victoria, Málaga, España.

Hipertension Y Riesgo Vascular
|July 9, 2024
PubMed

Insights

Celiac disease (CD) is linked to hypercoagulability, with increased antiphospholipid antibodies (AAF) observed in CD patients. This suggests a potential relationship between CD and antiphospholipid syndrome (APS), raising thrombotic event risks.

Area of Science:

  • Immunology
  • Gastroenterology
  • Hematology

Background:

  • Celiac disease (CD) is associated with a hypercoagulable state.
  • Antiphospholipid antibodies (AAF) are frequently elevated in CD patients.
  • Antiphospholipid syndrome (APS) involves a risk of thrombotic events.

Observation:

  • This study presents a descriptive case of a patient diagnosed with both CD and APS.
  • The co-occurrence of these conditions highlights a potential interrelation.

Findings:

  • The simultaneous diagnosis of CD and APS in this patient underscores their potential link.
  • Elevated AAF in CD patients may indicate an increased susceptibility to APS.

Implications:

  • Understanding the interplay between CD and APS is crucial for managing thrombotic risk.
  • Further research into the shared mechanisms could lead to improved patient outcomes.
  • This case emphasizes the importance of screening for APS in celiac disease patients.

Keywords:
Antiphospholipid syndromeCeliac diseaseCeliaquíaHipercoagulabilidadHypercoagulabilitySíndrome antifosfolípido

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