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Updated: Jun 21, 2025

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
Published on: October 12, 2016
[Secondary defect coverage and functional reconstruction]
Stephan Thunich1, Nicco Krezdorn2,3
1Abteilung für Plastische- und Brustchirurgie, Seeland Universitätsklinik, Sygehusvej 10, 4000, Roskilde, Dänemark.
Abstract:
Secondary reconstruction in trauma surgery is crucial for restoring both functional and esthetic results in patients with complex defects. Established reconstructive techniques in plastic surgery offer a wide range of options for an effective treatment. This applies not only to covering large defects with free flaps but especially also for the functional reconstruction of bony, neural and musculotendinous impairments. Advances in the fields of microsurgery and 3D printing show innovative approaches to further improve the therapeutic options. A multidisciplinary approach, requiring close collaboration between trauma and plastic surgeons, is necessary to optimize treatment plans and outcomes. The effective management of complications and qualified postoperative care are essential for the success of reconstructive measures.
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